Talk:Lamotrigine

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Use in PTSD[edit]

While I have great respect for the work done by Cochrane, I have seen far too many patients improve with PTSD symptoms especially if they have co-occurring bipolar disorder. The avoidance doesn't usually improve, but the irritability, impulsivity, and anger/hyper-arousal usually improve. I'm unaware of any RCTs or much work in general done with this, but a number of colleagues have noticed the same. — Preceding unsigned comment added by 132.239.142.131 (talk) 23:56, 13 January 2021 (UTC)[reply]

Sleep disturb % is misstated.[edit]

Not, "However, a retrospective study of 109 patients' medical records found that 6.7% of patients experienced an "alerting effect" resulting in intolerable insomnia, for which the treatment had to be discontinued. (65)"

It's only 6.4%.

65) Sadler M (March 1999). "Lamotrigine associated with insomnia". Epilepsia. 40 (3): 322–5. doi:10.1111/j.1528-1157.1999.tb00712.x. PMID 10080513. S2CID 43902298. 98.144.238.191 (talk) 17:28, 29 June 2022 (UTC)[reply]

How to take this medication. Empty stomach? With food? Time of day? Etc. 68.66.100.253 (talk) 14:36, 8 January 2024 (UTC)[reply]